Answer: MAIN
MAIN is a crossword puzzle answer that we have spotted 105 times.
Referring Clues:
- With 39-Across, featured boxing match
 - Water conduit
 - Predominant
 - Chief
 - Water source
 - Kind of a drag
 - __ Line (fashionable Pennsylvania area)
 - Common street name
 - Central
 - Water pipe
 - Street with stores, usually
 - Foremost
 - Duct
 - Bounding site?
 - It may be bounding
 - Cardinal
 - Sinclair's street
 - Central street
 - Primary
 - Most important
 - Key
 - Paramount
 - Spanish ___
 - With 59-Across, A-B-C-A in the illustration
 - Street that may be a U.S. highway
 - Water duct
 - Large water pipe
 - Kind of a drag?
 - Water carrier
 - Principal
 - Everystreet
 - Lead
 - Big water pipe
 - Water route
 - Large pipe
 - Wide passageway for water
 - Primary sail
 - High seas
 - Most-important
 - It might cross 1st, 2nd and 3rd
 - Big drag?
 - Word with drag or squeeze
 - Might's partner
 - Might's partner
 - Central street name
 - Anytown, USA street
 - Big pipe
 - "___ Street" (1920 Sinclair Lewis novel)
 - Primary water pipe
 - Disneyland street
 - Alternative name for 1st Street, often
 - Water bearer, maybe
 - Principle
 - Most significant
 - Frankfurt's river
 - Portage and _________
 - Anytown, USA, street
 - Heritage river in Newfoundland
 - Popular street name
 - Major water line
 - Newfoundland heritage river
 - Disneyland street that ends at Sleeping Beauty Castle
 - "The ___ event"
 - Leading
 - "___ Street"
 - Street one block over from Second, maybe
 - Common parade street
 - Important street
 - Ocean
 - Kind of attraction
 - Squeeze starter
 - Companion of might
 - Street likely to have the most stoplights
 - Street through the middle of town
 - Street in a Sinclair Lewis title
 - Chief or primary
 - Its state quarter has a lighthouse
 - Open ocean
 - Disney World's ___ Street U.S.A.
 - Important pipe
 - Type of drag
 - Disneyland's ___ Street USA
 - Principal line
 - Primo
 - Common downtown street name
 - Major water pipe
 - Central, as a street
 - Principal water line
 - Prevailing
 - Not peripheral
 - Primary pipe
 - Water ___
 - Small-town parade street
 - Word with drag or sail
 - Major water source
 - Most common street name in the U.S.
 - Water line
 - ___ course (entree)
 - Not supporting, perhaps
 - ___ squeeze
 - Course opener?
 - Ocean, poetically
 - ___ attraction (star of the show)
 - One's primary character, in video game lingo
 - Street name in the center of town
 
Last Seen In:
- New York Times - October 06, 2025
 - LA Times - October 05, 2025
 - LA Times - October 04, 2025
 - New York Times - August 23, 2025
 - USA Today - June 11, 2025
 - New York Times - May 06, 2025
 - New York Times - April 25, 2025
 - LA Times - March 02, 2025
 - LA Times - January 18, 2025
 - LA Times - December 22, 2024
 - LA Times - December 13, 2024
 - New York Times - November 10, 2024
 - USA Today - October 10, 2024
 - New York Times - June 26, 2024
 - LA Times - October 04, 2023
 - New York Times - April 14, 2023
 - New York Times - March 24, 2023
 - New York Times - January 16, 2023
 - USA Today - January 04, 2023
 - New York Times - October 03, 2022
 
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