Answer: LISA
LISA is a crossword puzzle answer that we have spotted 290 times.
Referring Clues:
- One of "The Simpsons"
 - Daughter of Homer
 - "The Official Preppy Handbook" author Birnbach
 - "Mona ___"
 - One of TV's Simpsons
 - Daughter of Homer and Marge
 - One of the Simpsons
 - "Yanks" star Eichhorn
 - Actress Kudrow
 - Actress Bonet
 - Soprano ___ Della Casa
 - Oliver's wife on "Green Acres"
 - Kudrow of "Friends"
 - Sax-playing Simpson
 - A Simpson
 - Phoebe's portrayer on "Friends"
 - A Simpson sister
 - 1990's pop singer Stansfield
 - "The Simpsons" saxophonist
 - With 49-Across, singer with the 1997 hit "I Do"
 - "Stay" singer ___ Loeb
 - Heroine of Tchaikovsky's "Pique Dame"
 - Soprano Saffer
 - Elvis's daughter ___ Marie
 - Sister of Bart Simpson
 - Sen. Murkowski of Alaska
 - Phoebe's player on "Friends"
 - "The Simpsons" brainiac
 - "I'm Not ___," 1975 #1 country hit by Jessi Colter
 - Ali's woman
 - Precursor of the Apple Macintosh
 - Alaska senator Murkowski
 - Marge's TV daughter
 - "The Simpsons" girl
 - Bart Simpson sister
 - Kudrow or Bonet
 - Pop singer Loeb
 - "Stay (I Missed You)" singer Loeb
 - Kudrow who's among "Friends"
 - Folk rocker Loeb
 - The smartest Simpson kid
 - Mona ___
 - Simpson child
 - Ms. Kudrow
 - The vegetarian Simpson
 - Phoebe portrayer on "Friends"
 - The middle Simpson child
 - The middle Simpson sibling
 - Elvis's daughter
 - Sister of Bart and Maggie
 - Bart Simpson's sis
 - Simpson with eight hair spikes
 - Kudrow of "Analyze This"
 - Vegetarian Simpson
 - Edelstein of "House"
 - Old Apple computer
 - Repeated, singer who sang with Cult Jam
 - Brainy Simpson
 - Bart Simpson's brainy sister
 - "The Official Preppy Handbook" editor Birnbach
 - Character on "The Simpsons" voiced by Yeardley
 - Singer Stansfield
 - Actress Rinna
 - Sister of Bart
 - Lopes of TLC
 - "House" actress Edelstein
 - Gilda Radner "SNL" character Loopner
 - Name of the created woman in "Weird Science"
 - Insult comic Lampanelli
 - Astronaut Nowak in 2007 news
 - "Stay" singer Loeb
 - Suspense novelist Gardner
 - Simpson girl
 - Simpson with a 159 IQ
 - Kudrow of "Analyze That"
 - Unsuccessful 1980s Apple computer
 - Homer's daughter
 - Singer __ Marie Presley
 - Bart Simpson's sister
 - ''The Simpsons'' girl
 - ''Simpsons'' daughter
 - Kudrow of ''Friends''
 - Homer and Marge's middle child
 - Mrs. Oliver Wendell Douglas
 - ''Mona __''
 - Maggie's older sister
 - ''Simpsons'' sister
 - Da Vinci subject
 - ''Simpsons'' kid
 - ''Rear Window'' heroine
 - See 32 Down
 - ''The Simpsons'' kid
 - Hartman or Rinna
 - Simpson sibling
 - One of Bart's sisters
 - Simpson with a high IQ
 - Elvis’ daughter ___ Marie
 - Da Vinci model
 - Maggie Simpson's sister
 - Co-star with Courteney and Jennifer
 - Mona that hangs around
 - Famous portrait model name
 - The King's daughter
 - Mona that just hangs around
 - Bart's animated sister
 - Animated Simpson
 - "The Simpsons" kid
 - A "Friends" real name
 - Mona ____
 - Animated sax player
 - First name among the "Friends" cast
 - The brainy Simpson
 - Bart and Maggie's sister
 - Elvis' daughter
 - "Green Acres" wife
 - Springfield kid
 - "Friends" star Kudrow
 - Bart's sister
 - Bart's sister on "The Simpsons"
 - Maggie's sister
 - Bart Simpson's kid sister
 - Actress Edelstein of TV's "House"
 - Simpson in Springfield's Mensa chapter
 - "The Simpsons" daughter
 - "Mona" ___ (famous painting)
 - Bonet or Loeb
 - Sax-playing Simpson sibling
 - "Mona __ Smile": 2003 film
 - Dr. Cuddy on "House"
 - "Simpsons" kid
 - "Friends" co-star Kudrow
 - "Friend" of Jennifer and Courteney
 - ElvisÂ’ daughter ___ Marie
 - Singer ___ Marie Presley
 - "Mona ___ Smile": 2003 film
 - Simpson kid
 - WNBA's Leslie
 - "Simpsons" daughter
 - "Simpsons" sister
 - "Rear Window" heroine
 - "The Simpsons" genius
 - Sister of Maggie and Bart
 - Former "The View" panelist Ling
 - Overachieving Simpson
 - Overachieving Simpson
 - Brainy cartoon sister
 - Kudrow or Loeb
 - "Mona ___" (da Vinci work)
 - "The Simpsons'" character skilled at crosswords
 - Simpson with spiky hair
 - Presley progeny
 - Simpson voiced by Yeardley Smith
 - "Friends" costar Kudrow
 - Actress Bonet
 - Dudley's costar in "Arthur"
 - Grace's "Rear Window" role
 - Maggie and Bart's sister
 - Kudrow of 'Friends'
 - See 30-Across
 - Simpson or Kudrow
 - 'Mona ___'
 - Co-star of Jennifer and Courteney
 - Phoebe's portrayer
 - ___ Marie Presley
 - 'Marci X' star Kudrow
 - Singer Loeb
 - Kudrow of "Web Therapy"
 - See 44 Across
 - Three-time WNBA MVP ___ Leslie
 - Crossword-solving Simpson
 - "Friend" Kudrow
 - Marge and Homer's middle child
 - Simpsons middle child
 - Leonardo model
 - Greg's love on "House"
 - Actress Hartman
 - Bart's sis
 - "___ Many Splendored Thing"
 - Simpson whose middle name is Marie
 - Cat Stevens tune, "Sad ___"
 - Toon who plays a baritone sax
 - Vegetarian Simpson kid
 - Ms Vanderpump of Beverly Hills
 - Simpson who said "Beneath my goody two shoes lie some very dark socks"
 - "Simpsons" saxophonist
 - The Simpson who once got hooked on crosswords
 - Girl who's been 8 since 1987
 - Animated sister of Maggie
 - Early Apple computer name
 - Bart's intelligent sister
 - Smart Simpson
 - Rinna or Kudrow
 - Actress Vidal
 - ___ Leslie, three-time W.N.B.A. M.V.P.
 - One of the Presleys
 - "The Simpsons" second grader
 - Bart's toon sister
 - Maggie Simpson's sis
 - 'Mona '
 - Simpson who's a member of 12-Down
 - See 69-Across
 - Phoebe on "Friends"
 - Former L.A. Sparks All-Star ___ Leslie
 - When repeated, singer of the 1987 #1 hit "Head to Toe"
 - When repeated, Cult Jam singer
 - Simpson who lost a crossword contest in 2008
 - Kudrow of TV
 - Alther, author
 - Vanderpump of "Vanderpump rules"
 - Homer's middle child
 - Hall of Fame WNBA star ___ Leslie
 - Bart's brainy sister
 - One of the animated Simpsons
 - Songwriter Loeb
 - "Homer and ___ Exchange Cross Words" (2008 episode of "The Simpsons")
 - 1929 Gershwin song
 - Sister of Maggie Simpson
 - "Mona" ___
 - Bart's brainy sibling
 - Moral center of the Simpsons
 - Simpson with a high I.Q.
 - Crossword-solving girl on "The Simpsons"
 - Emmy-winning Kudrow
 - Model for Leonardo
 - Cartoon character who plays a saxophone
 - Kudrow of "The Boss Baby"
 - Toon named after one of Matt Groening's sisters
 - ESPN reporter Salters
 - Simpson with a pearl necklace
 - Leslie in the Women's Basketball Hall of Fame
 - See 92-Across
 - Bart's older sister
 - Leonardo subject
 - Most popular baby girl's name of the 1960s, per the Social Security Administration
 - Bonet of "the cosby show"
 - 1983 Apple computer with a girl's name
 - ___ Gherardini, memorable portrait subject
 - "Mona ___" (famous painting)
 - Simpson in Mensa
 - Lopes of R&B's TLC
 - Former WNBA star ___ Leslie
 - ___ Genova, author of "Still Alice"
 - Yeardley's role on "The Simpsons"
 - One of Bart Simpson's sisters
 - "The Comeback" star Kudrow
 - Legal thriller writer Scottoline
 - Daughter of Steve Jobs, after whom an early Apple computer was named
 - Singer Lopes dubbed "Left Eye"
 - Simpson the saxophonist
 - Name akin to Beth
 - Kudrow who played Phoebe on "Friends"
 - Bart's born-first sister
 - Edelstein of "The Kominsky Method"
 - Member of Blackpink
 - WNBA legend Leslie
 - Marge Simpson's oldest daughter
 - Vanderpump of Bravo's "Vanderpump Rules"
 - Younger sister of Bart
 - Simpson who is a Buddhist and a vegetarian
 - Da Vinci's "Mona ___"
 - ___ Cuddy, Dean of Medicine on "House"
 - When repeated, Cult Jam vocalist
 - "Mona ___," painting with an enigmatic smile
 - "The Simpsons" character who competed in a crossword tournament
 - Works in healthcare
 - Actress Lu
 - Basketball great Leslie
 - Leonardo Da Vinci's "Mona ___"
 - ___ "Left Eye" Lopes
 - "Snow Flower and the Secret Fan" novelist See
 - The ___ Rinna M&M
 - Three-time WNBA MVP Leslie
 - Simpson daughter voiced by Yeardley Smith
 - Simpson with an I.Q. of 159
 - Actress Edelstein
 - Basketball Hall of Famer Leslie
 - Her first word was "Bart"
 - Simpson daughter
 - Salters of ESPN
 - ___ Leslie, Los Angeles Sparks star in the Basketball Hall of Fame
 - "Abbott Elementary" actress ___ Ann Walter
 - Middle Simpson kid
 - Simpson who plays the sax
 - "Lady Tan's Circle of Women" novelist See
 - Novelist Scottoline known for legal thrillers
 - WNBA great Leslie
 - Member of K-pop's Blackpink
 - TV journalist Ling
 - Lead rapper for Blackpink
 - Daughter of 52-Across
 
Last Seen In:
- USA Today - October 30, 2025
 - LA Times - September 11, 2025
 - USA Today - August 22, 2025
 - LA Times - June 08, 2025
 - LA Times - March 09, 2025
 - USA Today - February 28, 2025
 - New York Times - January 09, 2025
 - New York Times - December 31, 2024
 - LA Times - November 18, 2024
 - LA Times - October 17, 2024
 - LA Times - June 20, 2024
 - LA Times - June 16, 2024
 - LA Times - June 12, 2024
 - USA Today - May 24, 2024
 - LA Times - April 20, 2024
 - New York Times - April 01, 2024
 - LA Times - March 31, 2024
 - LA Times - February 20, 2024
 - USA Today - January 29, 2024
 - New York Times - January 13, 2024
 
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