Answer: HOUSTON
HOUSTON is a crossword puzzle answer that we have spotted 22 times.
Referring Clues:
- George Bush's home now
 - Two-time president of Texas
 - Astronauts' contact
 - Sam, who led the struggle to win control of Texas from Mexico
 - Texas president Sam
 - First word spoken to earth from the lunar surface
 - Rice University site
 - First Republic of Texas president
 - Largest city in Texas
 - Addressee of the 4/14/1970 message "we've had a problem"
 - Texas city
 - Brown's former partner
 - Home of the Rockets
 - "The Bayou City"
 - Home base for many a mission
 - Rice University home
 - Astros' home
 - Fourth-most populous U.S. city
 - Rice University city
 - Sam who won at the Battle of San Jacinto
 - Wealthy TV sleuth Matt
 - First word spoken on the moon, 1969
 
Last Seen In:
- New York Times - December 01, 2022
 - LA Times - July 24, 2020
 - New York Times - April 10, 2020
 - USA Today - December 03, 2018
 - LA Times - December 03, 2015
 - Universal - July 03, 2015
 - King Syndicate - Thomas Joseph - February 28, 2015
 - King Syndicate - Eugene Sheffer - August 12, 2014
 - New York Times - September 01, 2013
 - Netword - June 23, 2012
 - Universal - December 19, 2011
 - Post Puzzler - November 06, 2011
 - USA Today - August 03, 2011
 - LA Times - December 19, 2010
 - King Syndicate - Thomas Joseph - May 29, 2010
 - New York Times - September 30, 2007
 - Netword - February 04, 2007
 - LA Times - June 20, 2006
 - King Syndicate - Thomas Joseph - May 13, 2005
 - New York Times - October 30, 1999
 
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